metanogenic archaea (produce methane gas from methanol with hydrogen as the electron donor) inhabiting human gut. The balance of methanogens and other microbes within the human gut plays a role in the health and disease of the animal they inhabit. The prevalence of M. luminyensis significantly increases with age, contrary to M. smithii and M. stadtmanae. Methanomassiliicoccus luminyensis B10 is able to deplete trimethylamine (TMA), by reducing it with hydrogen for methanogenesis and was proposed to be used as treatment (archaebiotic) for metabolic disorders.
Methanomassiliicoccus
Dridi, B., Fardeau, M.-L., Ollivier, B., Raoult, D., and Drancourt, M. ."The antimicrobial resistance pattern of cultured human methanogens feflects the unique phylogenetic position of Archaea.." J. Antimicrob. Chemother. (2011) 66:2038-2044.
Dridi, B., Fardeau, M.L., Ollivier, B., Raoult, D., and Drancourt, M. ."Methanomassiliicoccus luminyensis gen. nov., sp. nov., a methanogenic archaeon isolated from human faeces.." Int. J. Syst. Evol. Microbiol. (2012) 62:1902-1907.
Gorlas A, Robert C, Gimenez G, Drancourt M, Raoult D. Complete genome sequence of Methanomassiliicoccus luminyensis, the largest genome of a human-associated Archaea species. J Bacteriol. 2012 Sep;194(17):4745. doi: 10.1128/JB.00956-12.
Genome Sequence of “Candidatus Methanomethylophilus alvus” Mx1201, a Methanogenic Archaeon from the Human Gut Belonging to a Seventh Order of Methanogens
Brugère JF, Borrel G, Gaci N, Tottey W, O'Toole PW, Malpuech-Brugère Archaebiotics: proposed therapeutic use of archaea to prevent trimethylaminuria and cardiovascular disease
Gut Microbes. 2014 Jan-Feb;5(1):5-10. doi: 10.4161/gmic.26749. Epub 2013 Oct 31. (full text)
Characterization and detection of a widely distributed gene cluster that predicts anaerobic choline utilization by human gut bacteria
Dridi B, Henry M, Richet H, Raoult D, Drancourt M. Age-related prevalence of Methanomassiliicoccus luminyensis in the human gut microbiome. APMIS. 2012 Oct;120(10):773-7. doi: 10.1111/j.1600-0463.2012.02899.x. Epub 2012 Mar 23.
- Candidatus Methanomassiliicoccus intestinalis
- Methanomassiliicoccus luminyensis
- Methanomassiliicoccus sp. 138
- Methanomassiliicoccus sp. 142
- Methanomassiliicoccus sp. 486
- Methanomassiliicoccus sp. N89-2
- Methanomassiliicoccus sp. P27
- environmental samples
Dridi, B., Fardeau, M.-L., Ollivier, B., Raoult, D., and Drancourt, M. ."The antimicrobial resistance pattern of cultured human methanogens feflects the unique phylogenetic position of Archaea.." J. Antimicrob. Chemother. (2011) 66:2038-2044.
Dridi, B., Fardeau, M.L., Ollivier, B., Raoult, D., and Drancourt, M. ."Methanomassiliicoccus luminyensis gen. nov., sp. nov., a methanogenic archaeon isolated from human faeces.." Int. J. Syst. Evol. Microbiol. (2012) 62:1902-1907.
Gorlas A, Robert C, Gimenez G, Drancourt M, Raoult D. Complete genome sequence of Methanomassiliicoccus luminyensis, the largest genome of a human-associated Archaea species. J Bacteriol. 2012 Sep;194(17):4745. doi: 10.1128/JB.00956-12.
Genome Sequence of “Candidatus Methanomethylophilus alvus” Mx1201, a Methanogenic Archaeon from the Human Gut Belonging to a Seventh Order of Methanogens
Brugère JF, Borrel G, Gaci N, Tottey W, O'Toole PW, Malpuech-Brugère Archaebiotics: proposed therapeutic use of archaea to prevent trimethylaminuria and cardiovascular disease
Gut Microbes. 2014 Jan-Feb;5(1):5-10. doi: 10.4161/gmic.26749. Epub 2013 Oct 31. (full text)
Characterization and detection of a widely distributed gene cluster that predicts anaerobic choline utilization by human gut bacteria
Dridi B, Henry M, Richet H, Raoult D, Drancourt M. Age-related prevalence of Methanomassiliicoccus luminyensis in the human gut microbiome. APMIS. 2012 Oct;120(10):773-7. doi: 10.1111/j.1600-0463.2012.02899.x. Epub 2012 Mar 23.
