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AURAMETRIX

The Smell of Christmas

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How does Christmas smell like? 

Like cinnamon! So say studies by European scientists  [1-3]. And even though the smell of cinnamon is described as "pungent" (besides "warm", 'sweet", and "spicy"), it fires up our brains, evoking a joyful Christmas mood and making us more generous. 

Cinnamon is classified as a stimulant. Smelling and tasting cinnamon could enhance attention and virtual recognition memory [4], at least in comparison to smells of peppermint, jasmine or cherries. In addition to its many healthy properties - like fighting E.coli in unpasteurized juices, lowering concentration of  fasting glucose, triglycerides, and total cholesterol - Cinnamon can make you feel fuller for longer [5]. So for those of us hoping to lose some weight - a cinnamon-flavored floss would be a good replacement for a Christmas desert.

Aggregate correlations - aka experience of the crowds analyzed in Aurametrix - tell many good things about Cinnamon. For example, that it led to less severe joint pain and helped with bad breath. Although - in higher concentrations - it was the reason of a yellowish skin.

Unfortunately for those with digestive problems, other Christmas-flavored foods seemed to have more side effects. Aurametrix correlations for Apple tell that exceeding sensitivity thresholds can lead to gas, fecal and musty smell (was this why an apple a day kept the doctor away?). Too much orange was associated with bloating, indigestion and yellow stool.  Pumpkin, on the other hand, lead to slightly better flavored gas!

With more daily observations entered by the users, Aurametrix will make more correlations between wellbeing and food flavors. But for now -

Merry Christmas! And let's smell some cinnamon!



REFERENCES

1. Seo HS, Buschhüter D, & Hummel T (2009). Odor attributes change in relation to the time of the year. Cinnamon odor is more familiar and pleasant during Christmas season than summertime. Appetite, 53 (2), 222-5 PMID: 19576937

2. Martin Lindström, Philip Kotler. Brand Sense: Sensory Secrets Behind the Stuff We Buy. Simon and Schuster, Feb 2, 2010

3. Idle JR. Christmas gingerbread (Lebkuchen) and Christmas cheer--review of the potential role of mood elevating amphetamine-like compounds formed in vivo and in furno. Prague.Med Rep. 2005;106(1):27-38.

4. Phillip Zoladz.  2003-2004 Allyn & Bacon Award Abstracts. Impact of the Chemical Senses on Augmenting Memory, Attention, Reaction Time, Problem Solving, and Response Variability: The Differential Role of Retronasal Versus Orthonasal Odorant Administration

5. Hlebowicz, J., Hlebowicz, A., Lindstedt, S., Bjorgell, O., Hoglund, P., Holst, J., Darwiche, G., & Almer, L. (2009). Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects American Journal of Clinical Nutrition, 89 (3), 815-821 DOI: 10.3945/ajcn.2008.26807

6. Khan A, Safdar M, Ali Khan MM, Khattak KN, Anderson RA. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215–8.

7. Catherine Ulbricht, Erica Seamon, Regina C. Windsor, Nicole Armbruester, J. Kathryn Bryan, Dawn Costa, Nicole Giese, Joerg Gruenwald, Ramon Iovin, Richard Isaac, Jill M. Grimes Serrano, Shaina Tanguay-Colucci, Wendy Weissner, Heeja Yoon, and Jie Zhang. An Evidence-Based Systematic Review of Cinnamon (Cinnamomum spp.) by the Natural Standard Research Collaboration.  Journal of Dietary Supplements, December 2011, Vol. 8, No. 4 : Pages 378-454 (doi: 10.3109/19390211.2011.627783)
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Can Software Help to Change Healthcare?

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Apps, apps and more apps. Software is everything and everything runs on software. 

Almost every industry in the U.S. has been disrupted by software. The health care field is not one of them.

Easily accessible consumer information makes everyone a little bit doctor. Emerging portable diagnostic devices will strengthen the transition. Are we up to it?

Not yet.

A large majority of people want to own their health information. Many want to store it online and have better control over it. Yet, most people don't want any extra work associated with updating and maintaining it. As public health record (PHR) expert Jim Tate said: 

"My 'dream PHR' continues to evolve. What I want now is a elegant interface which gives me a real time dynamic look into my record located somewhere in the stratosphere. I don’t want to have to do anything. Please don’t ask me to input anything or make more than 2 or 3 decisions. Make it simple, intuitive, powerful, and available on the internet and I will use it. Maybe."

Yes, we are inherently lazy, always trying to find shortcuts and reduce the amount of work to get a task done. Why spend time creating and maintaining our own records when a doctor can do it for us? Or even better, why not just live and enjoy life before we get sick? 

Problem is, most of us at various stages throughout life suffer from subtle conditions like food sensitivities or allergies that doctors can't easily diagnose. They're relatively minor in severity, but if managed properly our lives would be a lot better off. So maybe all we need is a doctor who's just a mobile app away, always ready to answer our questions for free.

But will these legions of online doctors have enough insight into our everyday lives to know what we eat, what we breath, and what it is we're not saying to form an expert opinion?

Not likely. Even if we could wear mobile devices - always on, always connected, counting our steps, cataloging our night sweats, and equipped with miniature cameras to photograph what we eat - would the doctors be able to process all that information to form a useful diagnosis?

Aurametrix is an advanced analysis tool that correlates our symptoms, reactions and feelings based on what we enter into the system about our diet, exercise and conditions. Results from early usage of the tool show that even occasional sparse information - entered on days we feel better or worse than average - if properly evaluated can provide a snapshot of our health with sufficient insight to connect the dots to better health.  It's a form of collective intelligence that's already providing interesting discoveries without the need for us to know all the details. For example, it already knows what our foods consist of, how our daily activities or feelings align with past events, and that there are commonalities among many different things. 

The future is already here but are we ready for the future?


REFERENCES

Archer N, Fevrier-Thomas U, Lokker C, McKibbon KA, & Straus SE (2011). Personal health records: a scoping review. Journal of the American Medical Informatics Association : JAMIA, 18 (4), 515-22 PMID: 21672914

Kim J, Bates DW. Analysis of the definition and utility of personal health records using q methodology. J Med Internet Res. 2011 Nov 29;13(4):e106.

Geissbuhler A, Kimura M, Kulikowski CA, Murray PJ, Ohno-Machado L, Park HA, Haux R.
Confluence of disciplines in health informatics: an international perspective. Methods Inf Med. 2011 Dec 6;50(6):545-55.

Macedo LG, Maher CH, Latimer J, McAuley JH. Feasibility of using Short Message Service (SMS) to collect pain outcomes in a low back pain clinical trial. Spine (Phila Pa 1976). 2011 Dec 3.

Lo Piparo E, Worth A, Manibusan M, Yang C, Schilter B, Mazzatorta P, Jacobs MN, Steinkellner H, Mohimont L. Use of computational tools in the field of food safety. Regul Toxicol Pharmacol. 2011 Aug;60(3):354-62. Epub 2011 May 12.

Benito PJ, Neiva C, González-Quijano PS, Cupeiro R, Morencos E, Peinado AB. Validation of the SenseWear armband in circuit resistance training with different loads. Eur J Appl Physiol. 2011 Dec 6. 

Yoshiaki Sugawara,Chie Sugimoto, Sachiko Minabe, Yoshie Iura, Mai Okazaki, Natuki Nakagawa, Miwa Seto, Saki Maruyama, Miki Hirano and Ichiro Kitayama. Use of Human Senses as Sensors. Sensors. 2009, 9(5), 3184-3204; doi:10.3390/s90503184

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The Road to Ammonia

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Why do I smell like Ammonia? This question, in thousands of variations, has been asked over and over again at every major question/answer site, especially teen, bodybuilding and athletic forums.
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The Internet provides plenty of opinions.
Medical sites talk about diseases like chronic kidney failure, hepatic cirrhosis or H. pylori infection. Fitness sites recommend drinking more water, reevaluating protein sources, nutrition programs (like Paleo diet) and eating more carbohydrates. ​
How exactly certain diets lead to particular odors? And what's the Science behind it? Ammonia may be formed during the alkaline hydrolysis and deamidation of proteins - by our own metabolism and the metabolism of microbes that call us home. If our kidneys can't handle the load of nitrogen, it's excreted as ammonia in sweat. Excretion increases 10 times as temperature goes from 70 to 100 Fahrenheit.

Aurametrix correlates users' actions and reactions based on information on diet and symptoms the system has. Preliminary correlations in the Aurametrix knowledge base show how exactly excess protein leads to ammonia-like odor.

But wait a minute - what about excess fat? 

An  example provided by one of our users is very interesting. The user logged a few foods he thought were contributing to odor. These were different odors according to the user - ranging from "Ammonia-like" to "Fishy", sharp, cloying and stale. Aurametrix, however, recognized that all these odors described by the user may be related to nitrogen-containing compounds.  When these three data points were analyzed along with four foods that the user did not associate with any odors, Aurametrix displayed only one result:
Based on your Aura entries, the following may be contributing to "Ammoniacal odor" in a 3 hour timeframe:
  • Hexadecanoic acid (when consumed more than 0.7 grams, up to 1.19)

Hexadecanoic acid - commonly known as Palmitic acid - is one of the most common saturated fatty acids in the Western diet. Palm oil and coconut oil contain especially high levels of this acid. What effect does this acid have on metabolism? It down-regulates glycose metabolism and protein metabolism, affecting calcium or mRNA binding proteins. So there may very well be a connection!
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