Every infection has a distinct odor. It could be associated with changes in the gut microbiome. Besides, circulating B-cells from our immune system are also producing chemical odors that appear after viral infection. T-cell and cytokine involvement is also possible. Infections can change body odor for the worse. PATM or MEBO conditions could begin after an infection and linger thereafter. READ MORE
Twenty years ago Trimethylaminuria (TMAU), also known as fish odor syndrome, was linked to mutations in the gene coding an enzyme named flavin-containing monooxygenase 3 (FMO3). As the list of associated SNPs kept growing, so was the list of other candidate genes.
The progress in developing useful diagnostic applications based on microbiome testing is still behind expectations. Nevertheless, microbiome-based diagnostic and therapeutic applications are possible and will be the next step.
MEBO is a complex condition and while some of the cases seem simpler, non-linear analysis approaches are better equipped to handle the task. And this creates new challenges regarding the existence of confounding factors.