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AURAMETRIX

Digestive health: Nov-Dec 2022

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December 24, 2022: Post-COVID Irritable Bowel Syndrome The COVID-19 pandemic has highlighted the potential link between infections and IBS

December 18, 2022: 
Pancreatitis after COVID-19 vaccines Acute pancreatitis is rare in patients with COVID-19, but can also happen after vaccination. Mild pancreatic inflammation is often clinically undetectable until resultant end-organ damage causes incipient clinical symptoms.

November 30, 2022: 
The Health Benefits of Mung Beans Low in calories, easy to digest legumes with antiinflammatory, cholesterol-lowering and antidiabetic properties
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September Vaccine Case Reports

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September 30, 2022: Vaccine-induced-pericarditis after COVID-induced myocarditis Previous myocarditis is not an absolute contraindication to vaccination, but clinicians must assess individual risk factors before counseling further doses.

September 29, 2022: Total hair loss after vaccination Many cases of males and females between the ages of 15 and 80 losing hair after COVID-19 vaccines were reported in the literature.

September 28, 2022: Neuropathy after COVID-19 Vaccination in a 21-year-old man Young man experienced near paralysis after vaccination

September 26, 2022: Quadruple-vaxxed 60-year-old man tests positive for COVID second time in 2 months Two consequtive infections during BA.5 reign

September 24, 2022: Breakthrough long COVID in a patient with rheumatoid arthritis 37-year-old woman experienced persistent headache and fatigue for over 6 weeks after SARS-CoV-2 infection and continued to test positive for 14 weeks post-infection despite no new exposures.

September 21, 2022: Designing food environment to improve behavior Personalized combination of interventions, individual psychology and activity environment along with a better integration of human element are needed for designing successful digital interventions to improve health-related behavior.

September 19, 2022: Vaccine-induced interstitial lung disease Autoimmune interstitial lung disease is associated with both increased reactogenicity and impaired immunogenicity to COVID-19 vaccines

September 18, 2022: COVID-19 vaccine-associated myositis Autoimmunity associated with vaccines may be related to specific HLA phenotypes, but the exact underlying mechanisms remain unclear.

September 15, 2022: Bipolar disorder after COVID-19 Mental health conditions are among the growing list of symptoms associated with post-COVID health issues. Presented case describes a 55-year-old patient with no previous mental illness who developed full-blown manic symptoms following a severe course of COVID-19.

September 11, 2022: Advanced age is associated with the risk of post-booster COVID-19 death Age was found to be the most important characteristic associated with the risk of death despite vaccination including additional booster dose.

September 7, 2022: Pediatric myocarditis after mRNA COVID-19 vaccination in Japan The proportion of individuals with myocarditis that visited a hospital in Japan was estimated to be 0.022% - remarkably higher than previously reported. Our study showed that the number is much higher since many individuals never officially consulted a medical professional.

September 6, 2022: 79-year old woman dies from anaphylaxis after vaccination 79-year old female with history of chronic obstructive pulmonary disease, emphysema and diabetes died 15 minutes after receiving an mRNA vaccine despite anaphylaxis treatment.

September 3, 2022: Psychosis following COVID-19 COVID-19 vaccination Psychiatric side effects associated with vaccines are possible.
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How are you feeding your microbiome?

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As we are gearing up for final stage of our clinical study  NCT03582826, we are looking at different subgroups of our participants based on their dietary intake, to find more precise, personalized and powerful solutions for everyone. 

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Unraveling the Mysteries of Mischievous Microbiome

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Science explains why some people smell worse than others despite keeping themselves squeaky clean. 

The body is crawling with microbes that have evolved with the person, depending on the innate metabolism, history of infections, microbiome swaps, diet and lifestyle. 

The body's ecosystem of microorganisms can increase the risk for dangerous diseases for which we have unreserved levels of sympathy. It can also lead to ​unlikable conditions such as unpredictable and embarrassing outbursts of odor emitting through the pores - odor so bad it ruins social lives and careers. 

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There is no cure for conditions responsible for odorous microbiomes. A rare disease TMAU (Trimethylaminuria) - an inborn error of choline metabolism that leads to the excessive excretion of foul-smelling trimethylamine (TMA) in the sweat and breath  - can sometimes be managed by unhealthy diet very low in choline. A purely-microbiome-caused case of armpit odor may be fixed by microbial transplantation. But research is still in its early stages and is mostly unfunded. 

Our community-led clinical trial was the first study attempting to find what is in common among individuals suffering from odor unexplained by known medical conditions such as TMAU. 

​We have demonstrated that symptoms described by participants are real - as they correlate with a number of laboratory tests. We have also proposed that there are at least two groups of participants with different genetics/medical histories (hence different microbiomes) that may require different types of treatments. 

Unfortunately publishing these results is very difficult - with no funding to cover publication fees and no "sex appeal" to get support from peers. (The article was submitted to the Journal of Participatory Medicine in February, but peer-reviewers still have not returned their reviews)
 
The preprint is now available at bioRxiv and raw results at Mendeley. Study results will be also available on the clinical trials site. 

We hope that the scientific community will look into our findings and support the underserved by their attention. Any comments or suggestions would be of great help!

REFERENCE
Irene S. Gabashvili (2017). Community-led research discovers links between elusive symptoms and clinical tests BiorXiv DOI: 10.1101/139014
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Seeing through the skin

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​Human skin emits light (albeit the glow is extremely weak) and a wide variety of small molecules that may be sometimes "sniffed" by dogs or even other humans. These chemicals tell a story about our health and wellness, things we eat and drink, touch and breathe. Mosquitoes use such emissions to assess our "attractiveness" from indicators such as Indoles (unpleasantly smelling but healthy "inner soil" biomarker) or carbon dioxide (amount of which correlates with the size of the person producing it) in the air. 

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Sampling air for health indicators is much less invasive than drawing blood and could be an invaluable diagnostic tool. Many applications of gas sensors have been proposed over decades ranging from sweat patches to sensorized garments. Where are we now? What is the 2016 state of the art?


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