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Sorbifer Durules

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Supplement, a vitamin C (ascorbic acid) and mineral iron (ferrous sulfate) combination preventing or treating low levels of iron in the blood that may be used for other conditions as determined by the doctor. 

Medical conditions that may interact with ferrous sulfate/vitamin c:
  • Pregnancy and breast-feeding
  • Allergies
  • Inflammation of the intestines, Crohn disease, digestive problems, ulcers, anemia, or a blood disease (eg, porphyria, thalassemia)
  • Multiple blood transfusions
  • Sickle cell disease or glucose-6-phosphate dehydrogenase (G6PD) deficiency
MEDICINES that MAY INTERACT with ferrous sulfate/vitamin c:
  • Doxycycline, mycophenolate, penicillamine, or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by ferrous sulfate/vitamin c

  • Take ferrous sulfate/vitamin c by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Swallow ferrous sulfate/vitamin c whole. Do not break, crush, or chew before swallowing.
  • Take ferrous sulfate/vitamin c with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking ferrous sulfate/vitamin c.
  • If you are also taking antacids, a bisphosphonate (eg, alendronate), cephalosporin (eg, cephalexin), methyldopa, penicillamine, quinolone (eg, ciprofloxacin), or tetracycline (eg, minocycline) along with ferrous sulfate/vitamin c, you may need to space the doses several hours apart. Ask your doctor or pharmacist how much time is needed between doses of ferrous sulfate/vitamin c and your other medicines.
  • Certain foods and drinks may decrease the amount of ferrous sulfate/vitamin c that works in your body. Ask your doctor or pharmacist how you should take ferrous sulfate/vitamin c if you consume whole grain breads or cereal, dairy products, coffee, or tea.
  • If you miss a dose of ferrous sulfate/vitamin c, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
  • Do not take large doses of vitamins while you use ferrous sulfate/vitamin c unless your doctor tells you to.
  • Do NOT take more than the recommended dose or take for longer than 6 months without checking with your doctor.
  • Ferrous sulfate/vitamin c has iron in it. Iron overdose is a leading cause of fatal poisoning in children younger than 6 years old. In case of an overdose, call a doctor or poison control center right away.
  • Diabetes patients - Ferrous sulfate/vitamin c may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.
  • Lab tests, including complete blood cell counts and blood iron levels, may be performed while you use ferrous sulfate/vitamin c. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Ferrous sulfate/vitamin c should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
Possible side effects of ferrous sulfate/ vitamin c:
Constipation; darkened or green stools; diarrhea; nausea; stomach upset.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting
Symptoms of overdose may include difficulty breathing; loss of consciousness; seizures; severe nausea; stomach pain; tarry stools; unusual tiredness; vomiting; weak, fast heartbeat.

Store ferrous sulfate/vitamin c at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep ferrous sulfate/vitamin c out of the reach of children and away from pets.
​
  • Sorbifer Durules brands - Egis, Romania; Egis, Russian Federation
  • Sorbifer brands -  Egis, Georgia; Egis, Slovakia; Egis Pharmaceuticals, Poland
  • Other Brands: Fero-Grad (Pharma Logistics, Belgium), Fero-Grad Vitamin C (Teofarma, France) Vitelle Irospan, Ferroplex (Teva, Lituania), Kendural (Teofarma, Switzerland), Timoferol (Elerte, Lebanon; Elerté, France), Feroplect (SIC BHFZ, Georgia), Ferrograd-C (Abbott, New Zealand; Abbott, Oman)
see how sorbifer affected others
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